salicylate, ibuprofen, ketoprofen, magnesium salicylate, naproxen sodium, and sodium salicylate. ‘‘Alcohol Warning’’ [heading in boldface type]: ‘‘If you consume 3 or more alcoholic drinks every day, ask your doctor whether you should take [insert acetaminophen and one nonsteroidal anti-inflammatory analgesic/antipyretic active ingredient—including, but not limited to aspirin, carbaspirin calci...

Sodium salicylate is one of the nonsteroidal antiinflammatory drugs and is clinically used for antiinflammation and chronic pain relief. In the present study, we investigated the actions of sodium salicylate on gamma-aminobutyric acid type A receptor (GABA(A)) current in cultured rat spinal dorsal horn neurons. Sodium salicylate was found to reduce GABA(A) current in a reversible and concentrat...

Introduction: The prostaglandin E2 (PGE2), a cyclooxygenase (COX) product, play critical roles in the synaptic plasticity. Therefore, long term use of COX inhibitors may impair the synaptic plasticity. Considering the wide clinical administration of aspirin and its unknown effects on information processing in the brain, the effect of aspirin and sodium salicylate on the short term synaptic p...

sodium salicylate containing microemulsions have been formulated, based on the previous phase diagram studies, using a pharmaceutically acceptable surfactant and oil. the effects of formulation variables on the release profile of the drug from microemulsion through intact rat skin were also determined experimentally. in this investigation, two commercially available lecithins (namely epikuron 2...

1. Sodium salicylate modifies the precipitation of normal rabbit serum protein by sodium tungstate, and partially inhibits the precipitation of horse serum euglobulin by rabbit antiserum. Sodium salicylate added to a system containing crystalline egg albumin and its antibody partly prevents the formation of precipitate, the degree of inhibition being related to the concentration of salicylate. ...

Previous studies by us suggested that luminally administered sodium salicylate blocks dihydroxy-bile acid-induced colonic secretion in the rat. In the present study, an in vivo rat cecal loop technique is employed to compare the effects of luminally administered and parenterally administered sodium salicylate upon chenodeoxycholic acid-induced colonic secretion. In our experiment, inoculation o...

Objective(s) Cyclooxygenases  (COXs) are known to play some roles in physiological mechanisms related to learning and memory. Since sodium salicylate is an inhibitor of COX, we have evaluated the effect of peripheral and intra-hippocampal administration of sodium salicylate on spatial learning and memory in male rats. Materials and Methods Male rats were studied in two groups; the first grou...

objective(s) cyclooxygenases  (coxs) are known to play some roles in physiological mechanisms related to learning and memory. since sodium salicylate is an inhibitor of cox, we have evaluated the effect of peripheral and intra-hippocampal administration of sodium salicylate on spatial learning and memory in male rats. materials and methods male rats were studied in two groups; the first group r...

Tetraphenyl-butadiene is a useful alternative to sodium salicylate as a fluorescent wavelength converter for detectors in the vacuum uv. Measurements of the fluorescence efficiency of TPB relative to sodium salicylate over the wavelength range 735-3160 A are presented, and the application of TPB coatings to image tube detectors is discussed. Over the entire wavelength range studied TPB had a hi...